 | Target patient group: Stage B and C of primary (degenerative)
mitral regurgitation; no specific guidelines given for secondary
(functional) MR.
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 | Indication:
 | Exercise hemodynamics with either Doppler echocardiography or
cardiac catheterization is reasonable in symptomatic patients with
chronic primary MR where there is a discrepancy between symptoms and the
severity of MR at rest (stages B and C) |
 | Exercise treadmill testing can be useful in patients with chronic
primary MR to establish symptom status and exercise tolerance (stages B
and C). |
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 | Contraindication: General contraindications for exercise stress
testing. |
 | Evidence: Class IIA; evidence B |
 | Monitoring: Supervision by physician or physician assistant as
per protocol for other stress tests. |
 | When to stop exercise (Positive exercise echo end-points in
mitral regurgitation):
 | Symptoms: Exercise-induced dyspnea |
 | MR specific echo parameters:
 | Worsening MR |
 | Increase in PA systolic pressure (specific cutoff value not given
in guidelines; exercise PASP > 60 mm Hg is used in some studies)
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 | Interpretation: A patient with a positive stress echo using
above criteria becomes a stage D patient and should be considered for MV
repair or replacement. |